Um sir?
Um sir? That is not a walker.
(Kim Jong-Il)
Picture by: dunno source. Caption by: Brooksbelle via Advanced Lol Builder
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Cheezburger Network Blog
first!
Somatostatin acts by the binding of the somatostatin receptor to inhibitory G proteins, which, in turn, lower cyclic AMP and reduce intra-cellular free calcium throughteffects on the voltage-sensitive calcium ion channel. The effects of lowered cyclic AMP appear to only partially account for the effects of somatostatin, however. Changes in calcium concentration are likely a crucial step in the process, probably acting via increased potassium ion conductance and resultant membrane hyperpolarization.
Dammit just because I decided to take my time…
The Henry Eckford was a small passenger-cargo steamboat built in New York in 1824. She is notable for being the first steamship in the world to be installed with a compound engine, almost fifty years before the technology would become widely adopted for marine use.
You need to click on “reply” underneath the comment, otherwise it doesn’t nest.
Maybe that wasn’t a reply to anything…maybe he or she just wanted to let us know about the Henry Eckford.
Nope – nesting fail on my part.
And my parts are male, for the record.
I’ve always wondered what’s this thing with the sunglasses…
For my money, the real psychoanalysis is to be done on the huge hats. I mean come on, they’re as tall as the heads they adorn!
They’re all Toads.
Link.
Analyze this hat… {link}
Uhhmmm… she’s TTQ?
That’s what I was thinking as well. What’s up with those?
They make them all look very small. (And I don’t mean ‘racist generalization that all Asians are small’, I mean they look like they’re about ten years old, wearing their daddy’s hats.)
It’s been ages since I laughed at a PK caption…
The Great Leader looks to be in absolutely magnificent health.
wow he looks like hes lost 75% of his body weight. Maybe he is dying like the rumors were saying.
He’ll die faster if he drowns… So *shhhhhhhh*
Either that or he’s about to be the latest NutriSystem advertising shill…
“I lost 70 pounds, and my mind, on NutriSystem. Call now, and I’ll throw in an AK-47 and a lifetime enlistment in the North Korean Army…for free!!!”
No, it’s gotta be TrimSpa. It’s just meth and meth in a neurotoxin. Hooray neurotoxins!
It’s TrimSpa, baby!!
Or is that too soon, too?
Mmmmm…..Neurotoxins…….Tangy
North Korean scientists decide to test the theory that sh!t floats…
You know you love the Icanhaz universe too much when you wake up and it makes your day to find your LOL on the homepage!! =)
Well done…one of the funniest I’ve seen in a while!!
Please, for love of everything good and decent, please push him in.
i hear that
Maybe he thinks he’s piloting a ship……?
lets hope it’s a submarine
mother goose u are so hilarious. LMAO! for real. this is the funniest shit tonite and comments by you by far.